Donna Trenton is a frustrated suburban housewife whose life is a turmoil after her husband learns about her having an affair. Brett Camber is a young boy whose only companion is a Saint-Bernard named "Cujo", who in turn is bitten by a rabid bat. Whilst Vic, Donna's husband is away on business, and thinking over his marital troubles, Donna and her 5-year-old son Tad take her Pinto to Brett Cambers' dad's car shop... the car fails, and "Cujo" is very, very sick...

Helen is the young girlfriend of good-looking Jackson Baring. When Helen gets pregnant and marries Jackson, they decide to move to his hometown, Kilronan, and have a baby there. But his mother Martha, who lives there, starts to do weird things, and obviously she's not too friendly to Helen.

Pregnant forensic psychologist Lydie Crane is hired to learn the truth behind the case of 16-year-old Stephanie Daley, who is accused of concealing her pregnancy and murdering her infant.